This page provides a standing resource for presentations by Dr. Steven Frese, PhD, an Assistant Professor in the Department of Nutrition at the University of Nevada, Reno and the University of Nevada, Reno School of Medicine.
Resources
These resources are provided as sources of independent information on the gut microbiome, probiotics, and probiotics
NIH – NCCIH National Center for Complementary and Integrative Health
International Scientific Association for Probiotics and Prebiotics
References
These peer-reviewed publications and/or government reports were cited in the presentation.
Armet, Anissa M., Edward C. Deehan, Aidan F. O’Sullivan, João F. Mota, Catherine J. Field, Carla M. Prado, Alice J. Lucey, and Jens Walter. 2022. “Rethinking Healthy Eating in Light of the Gut Microbiome.” Cell Host & Microbe 30 (6): 764–85. https://doi.org/10.1016/j.chom.2022.04.016.
Goel, Abhishek, Omprakash Shete, Sourav Goswami, Amit Samal, Lavanya C B, Saurabh Kedia, Vineet Ahuja, Paul W. O’Toole, Fergus Shanahan, and Tarini Shankar Ghosh. 2025. “Toward a Health-Associated Core Keystone Index for the Human Gut Microbiome.” Cell Reports 44 (3): 115378. https://doi.org/10.1016/j.celrep.2025.115378.
Li, Fuyong, Anissa M. Armet, Katri Korpela, Junhong Liu, Rodrigo Margain Quevedo, Francesco Asnicar, Benjamin Seethaler, et al. 2025. “Cardiometabolic Benefits of a Non-Industrialized-Type Diet Are Linked to Gut Microbiome Modulation.” Cell, January, S0092-8674(24)01477-6. https://doi.org/10.1016/j.cell.2024.12.034.
Berg, G., Rybakova, D., Fischer, D., Cernava, T., Vergès, M.C.C., Charles, T., Chen, X., Cocolin, L., Eversole, K., Corral, G.H. and Kazou, M., 2020. Microbiome definition re-visited: old concepts and new challenges. Microbiome, 8(1), pp.1-22.
Subramanian, S., Blanton, L.V., Frese, S.A., Charbonneau, M., Mills, D.A. and Gordon, J.I., 2015. Cultivating healthy growth and nutrition through the gut microbiota. Cell, 161(1), pp.36-48.
Kohl, K.D., Weiss, R.B., Cox, J., Dale, C. and Denise Dearing, M., 2014. Gut microbes of mammalian herbivores facilitate intake of plant toxins. Ecology letters, 17(10), pp.1238-1246.
Yatsunenko, T., Rey, F.E., Manary, M.J., Trehan, I., Dominguez-Bello, M.G., Contreras, M., Magris, M., Hidalgo, G., Baldassano, R.N., Anokhin, A.P. and Heath, A.C., 2012. Human gut microbiome viewed across age and geography. nature, 486(7402), pp.222-227.
Odamaki, T., Kato, K., Sugahara, H., Hashikura, N., Takahashi, S., Xiao, J.Z., Abe, F. and Osawa, R., 2016. Age-related changes in gut microbiota composition from newborn to centenarian: a cross-sectional study. BMC microbiology, 16(1), pp.1-12.
Duar, R.M., Henrick, B.M., Casaburi, G. and Frese, S.A., 2020. Integrating the ecosystem services framework to define dysbiosis of the breastfed infant gut: the role of B. infantis and human milk oligosaccharides. Frontiers in nutrition, 7, p.33.
Warner, B.B., Deych, E., Zhou, Y., Hall-Moore, C., Weinstock, G.M., Sodergren, E., Shaikh, N., Hoffmann, J.A., Linneman, L.A., Hamvas, A. and Khanna, G., 2016. Gut bacteria dysbiosis and necrotising enterocolitis in very low birthweight infants: a prospective case-control study. The Lancet, 387(10031), pp.1928-1936.
Gibson, G.R., Hutkins, R., Sanders, M.E., Prescott, S.L., Reimer, R.A., Salminen, S.J., Scott, K., Stanton, C., Swanson, K.S., Cani, P.D. and Verbeke, K., 2017. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nature reviews Gastroenterology & hepatology, 14(8), pp.491-502.
Kellow, N.J., Coughlan, M.T. and Reid, C.M., 2014. Metabolic benefits of dietary prebiotics in human subjects: a systematic review of randomised controlled trials. British Journal of Nutrition, 111(7), pp.1147-1161.
Beserra, B.T., Fernandes, R., do Rosario, V.A., Mocellin, M.C., Kuntz, M.G. and Trindade, E.B., 2015. A systematic review and meta-analysis of the prebiotics and synbiotics effects on glycaemia, insulin concentrations and lipid parameters in adult patients with overweight or obesity. Clinical Nutrition, 34(5), pp.845-858.
Hill, C., Guarner, F., Reid, G., Gibson, G.R., Merenstein, D.J., Pot, B., Morelli, L., Canani, R.B., Flint, H.J., Salminen, S. and Calder, P.C., 2014. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nature reviews Gastroenterology & hepatology, 11(8), pp.506-514.
Su, G.L., Ko, C.W., Bercik, P., Falck-Ytter, Y., Sultan, S., Weizman, A.V. and Morgan, R.L., 2020. AGA clinical practice guidelines on the role of probiotics in the management of gastrointestinal disorders. Gastroenterology, 159(2), pp.697-705.
Lewis, Z.T., Shani, G., Masarweh, C.F., Popovic, M., Frese, S.A., Sela, D.A., Underwood, M.A. and Mills, D.A., 2016. Validating bifidobacterial species and subspecies identity in commercial probiotic products. Pediatric research, 79(3), pp.445-452.
Vallabhaneni, S., Walker, T.A., Lockhart, S.R., Ng, D., Branch, I.D.P., Chiller, T., Melchreit, R., Brandt, M.E. and Smith, R.M., 2015. Fatal gastrointestinal mucormycosis in a premature infant associated with a contaminated dietary supplement—Connecticut, 2014. MMWR. Morbidity and mortality weekly report, 64(6), p.155.
van den Akker, C.H., van Goudoever, J.B., Shamir, R., Domellöf, M., Embleton, N.D., Hojsak, I., Lapillonne, A., Mihatsch, W.A., Canani, R.B., Bronsky, J. and Campoy, C., 2020. Probiotics and preterm infants: a position paper by the ESPGHAN Committee on Nutrition and the ESPGHAN Working Group for Probiotics and Prebiotics. Journal of Pediatric Gastroenterology and Nutrition.
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